2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W727481
    Cyetpyrafen
    		Inhibitor
    Cyetpyrafen is a pyrazole insecticide/acaricide with broad-spectrum insecticidal activity. Cyetpyrafen binds to DhelOBP4 (Ki = 4.95 μM) and DhelOBP21 (Ki = 5.51 μM) to mediate olfactory recognition in *Cryptolaemus montrouzieri*. Cyetpyrafen induces dose-dependent electroantennogram responses in *Cryptolaemus montrouzieri* and exhibits repellent effects on the species. Cyetpyrafen has bioaccumulative properties, is rapidly and passively absorbed by the roots of lettuce and rice, reaches a steady state within 24 h, preferentially accumulates in roots, and shows limited xylem/phloem translocation.
    Cyetpyrafen
  • HY-N14068
    Cytosaminomycin B
    		Inhibitor
    Cytosaminomycin B has anti-Eimeria Tenella activity.
    Cytosaminomycin B
  • HY-N8374
    Pheanthine
    		Inhibitor
    Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM).
    Pheanthine
  • HY-175345
    CYP3A4-IN-5
    		Inhibitor
    CYP3A4-IN-5 (Compound 5p) is a potent Leishmania major pteridine reductase 1 (Lm PTR1) inhibitor (IC50=12.77 µM). CYP3A4-IN-5 is promising for research of parasite infection.
    CYP3A4-IN-5
  • HY-180360
    Antiparasitic agent-34
    		Inhibitor
    Antiparasitic agent-34 (Compound NO.6913) is an orally active antiparasitic agent. Antiparasitic agent-34 exhibits anti-S. mansoni activity in mice.
    Antiparasitic agent-34
  • HY-125326
    Spinosyn D
    		Inhibitor 99.00%
    Spinosyn D is one of the major components of Spinosad (HY-138800). Spinosad is a natural pesticide that shows biological activity against a range of insects including Lepidoptera.
    Spinosyn D
  • HY-N14069
    Cytosaminomycin C
    		Inhibitor
    Cytosaminomycin C has anti-Eimeria Tenella activity.
    Cytosaminomycin C
  • HY-W631668
    Antileishmanial agent-34
    		Inhibitor
    Antileishmanial agent-34 (Fig. (9), compound 3) is an aurone with antileishmanial activity. Antileishmanial agent-34 against extracellular forms of Lmaj, Ldon, Linf and Lenr as well as against intracellular forms of Ldon (IC50 of <2 µg/mL).
    Antileishmanial agent-34
  • HY-B0433AR
    Quinine hydrochloride dihydrate (Standard)
    		Inhibitor
    Quinine (hydrochloride dihydrate) (Standard) is the analytical standard of Quinine (hydrochloride dihydrate). This product is intended for research and analytical applications. Quinine hydrochloride dihydrate (Qualaquin) is an orally active and can be used in anti-malarial studies. Quinine hydrochloride dihydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM.
    Quinine hydrochloride dihydrate (Standard)
  • HY-180388
    Stibophen
    		Inhibitor
    Stibophen is a potent antiparasitic agent is effective against Litomosoides carinii, Dipetalonema witei, and Brugia pahangi. Stibophen inhibits lactate accumulation and phosphofructokinases (PFK) activity in adult filariids. Stibophen also inhibits Ascaris and Hymenolepis diminuta PFK without inhibiting mammalian liver PFK. Stibophen can be used for the research of schistosomiasis and filariid infections.
    Stibophen
  • HY-136458R
    3-ANOT (Standard)
    		Inhibitor
    3-ANOT (Standard) is the analytical standard of 3-ANOT. This product is intended for research and analytical applications. 3-ANOT is a metabolite of Dinitolmide (a nitroamide coccidiostat commonly used in poultry production).
    3-ANOT (Standard)
  • HY-123192
    Uredofos
    		Inhibitor
    Uredofos is a broad-spectrum anthelmintic. Uredofos has anticestodal activity.
    Uredofos
  • HY-151217R
    Ipronidazole (Standard)
    		Inhibitor
    Ipronidazole (Standard) is the analytical standard of Ipronidazole. This product is intended for research and analytical applications. Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water.
    Ipronidazole (Standard)
  • HY-117908
    DSM267
    		Inhibitor
    DSM267 is a triazolopyrimidine inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), with an IC50 of 38 nM, while its IC50 against human DHODH exceeds 100000 nM. DSM267 is used for the in vitro systematic screening and characterization of the resistance evolution pathways of Plasmodium falciparum to DHODH inhibitors.
    DSM267
  • HY-W780189
    (rac)-Monepantel
    		Inhibitor 99.87%
    (rac)-Monepantel ((rac)-AAD1566) is the racemic form of Monepantel (HY-14774). Monepantel (AAD1566, NUZ-001), an antiparasitic agent, is an orally active mTOR inhibitor.
    (rac)-Monepantel
  • HY-100586R
    Ibuprofen L-lysine (Standard)
    Ibuprofen (L-lysine) (Standard) is the analytical standard of Ibuprofen (L-lysine). This product is intended for research and analytical applications. Ibuprofen ((±)-Ibuprofen) L-lysine is a potent orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen L-lysine inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen L-lysine is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen L-lysine can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
    Ibuprofen L-lysine (Standard)
  • HY-N0389R
    Columbin (Standard)
    		Inhibitor
    Columbin (Standard) is the analytical standard of Columbin. This product is intended for research and analytical applications. Columbin is an orally active diterpenoid furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects. Columbin selectively inhibits COX-2 (EC50=53.1 μM) over COX-1 (EC50=327 μM).
    Columbin (Standard)
  • HY-B0537A
    Pentamidine dihydrochloride
    		Inhibitor
    Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
    Pentamidine dihydrochloride
  • HY-108053
    CDRI-97/78
    		Inhibitor
    CDRI-97/78 is an antimalarial agent. CDRI-97/78 has phototoxicity and can induce cell apoptosis and G2/M phase arrest. CDRI-97/78 can be used for the research of infection.
    CDRI-97/78
  • HY-W016621
    3,4-Methylenedioxypropiophenone
    		Inhibitor 98.13%
    3,4-Methylenedioxypropiophenone (Compound 4) is an isomer of 3,4-methylenedioxyphenyl-2-propanone. 3,4-Methylenedioxypropiophenone has potent activity against leishmania.
    3,4-Methylenedioxypropiophenone
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.